The workshop will explore how concepts and technologies in RNA biology can merge with sleep and circadian rhythms to understand and discover new principles of human physiology.
A two-day international workshop will be held at the University of Surrey funded by the Institute of Advanced Studies. The workshop will explore how concepts and technologies in RNA biology can merge with sleep and circadian rhythms to understand and discover new principles of human physiology. Multidisciplinary approaches will be developed to investigate the mechanisms underlying sleep phenotypes in humans founding the basis for bench to bedside research.
We invite international leaders in the field of RNA biology as well as in sleep and circadian research. The meeting will provide a unique opportunity to discuss current knowledge in the respective fields and to elaborate how they can be integrated – in particular, how the translational control mediated by RNA-binding proteins/non-coding RNAs impact on the regulation of sleep and circadian rhythms.
A main objective of this workshop is to provide a platform to establish new interdisciplinary collaborations. The program is built on short oral presentations, a poster session and complemented with round table discussions to highlight priority areas and explore the potential for collaborative research.
CONFIRMED SPEAKERS
Frédéric Gachon, PhD, Nestlé Institute of Health Sciences SA, Switzerland
Regulation of mouse physiology by circadian clock-coordinated post-transcriptional modifications
Peggy Janich, PhD, Group David Gatfield, Center for Integrative Genomics (CIG), University of Lausanne, Switzerland
Comprehensive identification of rhythmic protein synthesis using ribosome profiling in mouse liver
Nicholas Lahens, PhD, Group John Hogenesch, Smilow Translational Research Center, University of Pennsylvania, USA
A circadian gene atlas in mammals: rhythms, drugs, and dark matter
Peter Meerlo, PhD, Faculty of Mathematics and Natural Sciences, Behavioural Physiology, Centre for Behaviour and Neurosciences, University of Groningen, The Netherlands
Consequences of mild sleep disruption: changes in pCREB expression, hippocampal function and memory formation
Anne Willis, PhD, Director, MRC Toxicology Unit, University of Leicester, UK
Control of protein synthesis following cell stress: the cold shock response
Kathryn Lilley, PhD, Director of Cambridge Centre for Proteomics, Cambridge Centre for Proteomics, Cambridge System Biology Centre, Wellcome Trust Stem Cell building, University of Cambridge, UK
Simultaneous and dynamic protein subcellular localization using mass spectrometry
Siniša Volarević, PhD, Head of Department of Molecular Medicine and Biotechnology, School of Medicine, University of Rijeka, Croatia
Ribosome biogenesis stress and p53 activation
Simon Archer, PhD, Reader in Chronobiology, Dept. Of Biochemistry and Physiology, Faculty of Health and Medical Sciences, University of Surrey
The effects of mistimed sleep on the human circadian transcriptome: lost in translation
ORGANISERS
Professor André Gerber, Computational and Systems Biology Research Group
Dr Nicolas Locker, Infectious Diseases Research Group
Dr Raphaelle Winsky-Sommerer, Sleep Chronobiology and Addiction Research Group
Please see the accompanying videos below for more information on this event.